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563 Monitoring and considerations include dose titration, initiating medications at low doses and gradually increasing to the maximum tolerated dose while monitoring efficacy and adverse effects

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da 0 a 2 anni sono consigliati 150 mg per kg di peso corporeo, da 2 a 6 anni 100 mg per kg, da 6 a 12 anni 75 mg per kg

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For example, supplementation with methylated B vitamins like folinic acid and vitamin B12 has shown to improve neurological and behavioral symptoms