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Individualized weight loss pharmacotherapy is recommended, based upon factors such as the specific characteristics of each weight loss medication, the presence of weight-related complications, and the medical history of the patient

This may be counterintuitive, as it seems clear that GLP-1 drugs have overwhelmingly positive effects on kidney function

Tirzepatide is a once-weekly injectable medication that activates receptors for two key gut hormones: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

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Medical groups like the American Diabetes Association and the American Heart Association have not raised major concerns about the heart risks of tirzepatide