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This condition can be either localized or widespread, and may be temporary or permanent
In vitro functional analyses confirmed their mature hepatocyte characteristics: they showed high transcription and protein expression of ALB, A1AT, CYP3A4, and CYP2C9, comparable to primary human hepatocytes (PHs)
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For example, a novel dual agonist of GLP-1/GIP receptors significantly increased BDNF levels in a mouse model of Parkinsons disease, induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration [53]