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The localization of SMAD2 to alveolar and airway tissue and the decreased TGF pathway activity seen with increasing emphysema severity support the hypothesis that a decrease in TGF pathway activity also contributes to emphysema pathogenesis

Se comercializa como reactivo de investigacin (RUO) para el estudio del metabolismo del dinucletido de nicotinamida y adenina (NAD+) y de la enzima nicotinamida N-metiltransferasa (NNMT), sobre la cual acta como inhibidor selectivo

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