This distinction is critical
doi:10.1002/mnfr.200500142 Trekli M, Buttle D, Guesdon F
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2.3 Mechanisms linking gut microbiota dysbiosis to hypothyroidism development Gut microbiota dysbiosis exerts significant impacts on multiple physiological systems, directly and indirectly exacerbating the pathogenesis of hypothyroidism through several interconnected mechanisms
And what we're targeting are naturally occurring gut hormones