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This complex can then be cleared by MRPs ( Moreover, Pt (IV) complexes have been intensively exploited in the development of GSH-responsive platinum drugs for controlled intracellular drug release

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Not everyone needs lifelong treatment, but some patients do benefit from longer use , especially if they have: Type 2 diabetes severe obesity repeated weight regain after stopping strong appetite/craving issues fatty liver PCOS with obesity and insulin resistance sleep apnea related to obesity multiple metabolic problems together In such patients, stopping too early may undo a lot of progress

doi: 10.1172/JCI31901