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Discussion This case involved vitamin B12 deficiency accompanied by deep sensory disturbance, but did not meet all classical diagnostic criteria for SCD

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The exact magnitude varies widely, from modest improvements to dramatic transformations depending on starting point and adherence

Indeed, because more than 100 proteins have been reported as TG2 substrates and because TG2 has broad substrate specificity, the GST tag could be crosslinked with a number of cellular proteins 21

Preclinical studies using animal models or neuronal cell cultures for conditions such as Parkinson's or Alzheimer's disease often measure tissue-specific GSH levels and the GSH/GSSG ratio as key biomarkers of oxidative damage