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Because of nicotine's high risk to health, nicotine patches are not recommended for clinical use in depression." [103] Though tobacco smoking is associated with an increased risk of Alzheimer's disease, [104] there is evidence that nicotine itself has the potential to prevent and treat Alzheimer's disease

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Mancia G, Schumacher H, Redon J, Verdecchia P, Schmieder R, Jennings G, et al