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A phase 2, multicenter, randomized, double-blind, placebo-controlled trial in the United States assessed the efficacy and safety of retatrutide in 338 adults aged 1875 years without diabetes but with obesity or overweight plus 1 weight-related condition for 48 weeks

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On the other hand, it is also clear that prolonged LC supplementation elevates fasting plasma TMAO [1618, 58, 59], compound supposed to be pro-atherogenic [61]

[PMC free article: PMC3825455] [PubMed: 20104221] (Details of 17 US cases of hepatotoxicity due to Hydroxycut in the US reported to the FDA between 2002 and 2009

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