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209 , e114477 (2022)

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Here we show morphine-induced constipation is mediated by a neural circuit from glutamatergic neurons in the paraventricular nucleus of hypothalamus (PVN Glu ) to acetylcholinergic neurons in the dorsal motor nucleus of the vagus (DMV Ach ), and subsequently to the small intestine in mice

Reads obtained from the blood samples described above were submitted to differential gene expression analysis across three comparisons: A) unstimulated blood samples before vaccination vs

Microglial and astrocytic proteins are preferentially elevated in the GCLC-KO mouse brain To uncover mechanisms leading to brain atrophy in GCLC-KO mice, we next performed a comprehensive analysis of protein expression by Liquid Chromatography-Mass spectrometry (LCMS) analysis using brain samples from 4-month-old GCLC-KO mice (Fig