PMID: 16962140 DOI: 10.1016/j.jns.2006.06.007 Keywords Soman (GD) Drug Class: Organophosphate Chemical Warfare Agent classified as a Nerve Agent Mechanism of Action: Inhibits the destruction of acetylcholine by cholinesterase Aging occurs within a half-life of only 2 minutes with soman Rapid aging can make it almost impossible to give pralidoxime rapidly enough to be beneficial after the first noticeable detection of symptoms of poisoning are felt, at which point a significant degree of aging has already occurred
ferroptosis has been proposed to be involved in COVID-19-related brain injury (Zhang et al., 2022)
PPAR has been shown to increase CAR expression [48,49], and this mechanism likely affects CAR target genes
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Depression ranges from everyday situational depression to major depressive disorder, characterized by profound hopelessness, helplessness, and biological symptoms such as sleep disorders and anhedonia and can be mimicked by symptoms of cirrhosis like HE and delirium, necessitating careful psychiatric differential diagnoses