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Apolipoprotein E (APOE) on chromosome 19 is another polymorphic protein and the allele APOE4 is the strongest genetic risk factor for Sporadic AD (Giri et al., 2016)

TLR signaling molecules, like mitogen-activated protein kinases (MAPK) and phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt), play fundamental roles in TLR-mediated cell proliferation and survival via reducing apoptosis and increasing time for viral replication (Li et al., 2010

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Resveratrol is a potent polyphenolic antioxidant compound produced by grapes and other plants for protection against pathogens