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Ambulatory blood pressure monitoring used in this study included blood pressure measurements every 30 minutes during the day and every hour at night, providing a more comprehensive assessment of blood pressure than in office or daily home blood pressure measurements

The FDA issued warning letters to multiple telehealth providers regarding marketing claims about compounded products

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Pooling across the field, a 2025 meta-analysis of seven randomized controlled trials, covering 456 participants, reported a standardized mean difference of -0.72 for wrinkle reduction, though the analysis noted high heterogeneity between studies and that roughly 40% of trials had industry funding both factors that warrant caution in interpreting the pooled effect size