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Due to the positive effects of IGF-1 on kidney regeneration after AKI, Matejka and Bengtsson investigated the effects of high-dose rhGH-therapy in an animal model of postischemic AKI [184]
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4 hours | Primary site of action: vascular signaling pathways, NO system | Key receptors: VEGFR2, eNOS | Research focus: gastrointestinal, tendons, inflammation | Endogenous: no (synthetic, derived from gastric juice) | Gene modulation: limited documentation TB-500 Half-life: approx
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Researchers isolated a specific fragment and created a stable, synthetic version
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