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Nevertheless, if beneficial effects on strength, similar to those demonstrated with GH79 can be shown, GH secretagogues could provide a well-tolerated clinical approach for treating or preventing sarcopenia, and perhaps, even forestall the inevitability of age-associated decline in function and independence. The decrease in GH/IGF-1 levels is thought to arise from insufficient stimulation, indicating a use it or lose it dilemma
Wanjek, C
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The results showed no toxicities or serious adverse events.[ref] Synthetic thymosin beta 4: A phase I safety trial using synthetic thymosin beta 4 at doses from 42 to 1260 mg for 14 days showed no toxicity or serious adverse events.[ref] Human clinical trials for specific conditions: Venous ulcers: Wounds that dont heal, such as venous ulcers, are a significant problem in older patients with limited mobility
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