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Upon restoration of the blood supply to the transplanted ovarian tissue, a substantial production of reactive oxygen species occurs, leading to vascular endothelial dysfunction, increased microvascular permeability, tissue edema, and an intensified inflammatory response

Moreover, glutathione is integral to immune function

The hot plate was maintained at the temperature of 55C, and experimental protocol as previously described (1, 26)

Llorens-Martin M et al (2013) GSK-3beta overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo