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Although aggressive weight loss improves glycemic and cardiovascular outcomes, it may increase transient gallstone formation

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John Wilding, professor of medicine in the Department of Cardiovascular and Metabolic Medicine at the University of Liverpool, said this was unsurprising, adding: Obesity is a chronic disease that usually relapses when treatment is stopped. Tricia Tan, professor of metabolic medicine, diabetes and endocrinology at Imperial College London/Imperial College Healthcare NHS Trust, said: There is increasing evidence that structured exercise is important to prevent weight regain after cessation of weight-loss drugs, but noted that this was not discussed in the study

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