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a 12-woman interstitial cystitis pilot (Lee, Walker & Ayadi, 2024)

Claims that compounded bioidentical HRT is safer or more effective than FDA-approved HRT are not supported by evidence from well-designed clinical studies, per ACOG, The Menopause Society, and NASEM

It also increases the production of luteinizing hormone, which aids in ovulation in females and the creation of testosterone in males

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This was always a potential concern, even back when I was frequently prescribing them