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In order to better grasp the degree of residue modification in chimera M8, we built a homology model to serve as a 3D base for further amino-acid substitution (Fig

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Regulation of other signaling pathways In addition to Nrf2 and insulin signaling pathways, lipoic acid was found to target other cell-signaling molecules thereby affecting a variety of cellular processes, including metabolism, stress responses, proliferation, and survival

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