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Nitric Oxide (NO) is one molecular mediator involved in both the inflammatory response [34] and oxidative damage [6, 35]
Cuando se observan en conjunto, muestran patrones que requieren una lectura ms amplia
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Rather than acting on a single pathway, effective strategies will likely need to address oxidative stress, mitochondrial dysfunction, neuroinflammation, calcium dysregulation, epigenetic remodelling and impaired neurotrophic signalling in an integrated manner [3,23,48]
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