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Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

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There are 3 types of underlying disease, depending on the clinical context in which it occurs: type A presents in the context of acute liver failure, type B in the context of porto-systemic shunting with no intrinsic liver disease, and type C in the context of cirrhosis with portal hypertension

In animal models, pravastatin demonstrated strong adjuvant action in a mouse model of human-like necrotic TB lung granulomas [60]