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Role of human glutathione S-transferases in the inactivation of reactive metabolites of clozapine

The characteristics include irregular sleepwake rhythm, sleep fragmentation, decreased nocturnal melatonin levels, increased light-induced melatonin suppression, delayed phase of the dim-light melatonin onset (DLMO), and abnormal melatonin synthesis, as reviewed by several authors [10, 50,51,52,53]

2003;1:e006

575 Furthermore, due to the heterogeneous distribution of hepatocytes, periportal hepatocytes, which are rich in GLS, play a predominant role in regeneration during CCl 4 -induced injury