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Also known as somatomedin C, it is a peptide hormone synthesized in the liver as the principal downstream mediator of growth hormone activity
Week 24 What you may notice: Clothes start fitting differently, especially around the midsection
A liver-specific knockout mouse exhibited some postnatal growth reduction, but not as severe as with global IGF knockout (Baker et al., 2013)
Some peptides may show diminished effectiveness over time, necessitating dose adjustments or alternative treatment approaches
Sandhu K, Flintoff K, Chatfield MD, Dixon JL, Ramm LE, Ramm GA, Powell LW, Subramaniam VN, Wallace DF
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