glp-1-based treatments approved for weight loss 2025 Weight-loss drugs such as Ozempic were in the headlines a lot in – and patent protections these drugs expire in some countries in 2026. In this edition of #PeriodicGraphics in @ The GLP-1 Revolution Continues

doi:10.1016/j.phrs.2023.107031 192

In real-world observations, individuals on GLP-1 therapies often fall below dietary benchmarks for: 3,5 Microminerals : magnesium, potassium, calcium, iron, and zinc Vitamins : D, A, E, K, B12, B1 (thiamine), and folate Macronutrients : protein and fiber Phytonutrients : including carotenoids and flavonoids Gastrointestinal effectsincluding nausea, bloating, early satiety, and evolving food aversionsfurther constrict intake variety and volume, amplifying the risk

experimental studies with other GLP-1 analogues (exendin-4 and liraglutide) have shown evidence of inhibition of oxidative stress, decreased apoptosis and prevalence of injured cells, decreased vascular proliferation, and increased c AMP levels in neurons and anti-inflammatory activity in microglial cells [67]

Blocking PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant liver cancer cells to B5G1, a new derivative of betulinic acid [319]

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