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This may involve exploring alternative dosing regimens, concomitant use of medications to protect facial adipose tissue, or the development of new GLP-1 receptor agonists with reduced lipodystrophy risk

Liu Q, Anderson C, Broyde A, Polizzi C, Fernandez R, Baron A et al (2010) Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure

Vegans and vegetarians are naturally at higher risk since B12 comes mainly from animal products