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Notably, the addition of 1 nM of vitamin B12 to blood cultures from individuals with VCD normalized the mRNA levels of CCL11 , upregulated the neuroprotective HGF , and, to a lesser extent, downregulated CSF2 and CXCL10

Effect sizes were generally large, with treated animals showing substantial improvements in healing time, tissue strength, functional recovery, and histological outcomes compared to untreated controls

Recommended storage and handling considerations include: Storage behavior may vary depending on reduced or oxidized form, residual moisture, container closure, and batch-specific documentation

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