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Loading phase: For patients without neurological involvement, the standard regimen is 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks (total of six injections)

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But even in those, the effect sizes are relatively small, and in the clinic the results are often more disappointing than the trials would suggest. Dr Whittle said due to the nature of fibromyalgia, there was unlikely to be a magic bullet or single receptor pharmacotherapeutic intervention that was broadly or substantially successful in most people with fibromyalgia