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In laboratory research, GHK-Cu is used as a biochemical tool to study copper-dependent signaling pathways, extracellular matrix (ECM) regulation, redox balance, and transcriptional modulation in controlled in vitro and preclinical experimental models
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Morphologically, PDM is almost indistinguishable from cutaneous metastatic melanoma (CMM), but it has a lower metastatic potential and a much better prognosis with a long-term survival rate of 80100%, compared with 24% for cutaneous metastatic melanoma stage IIIC, although deep penetration can occur (mean Breslow depth of 3.01 mm and Clark level III) [23]
