Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix
Genetic variability, unique disease characteristics, or unknown factors
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Cellular processes : Other studies are looking into the cellular processes of mitochondria (the power-producers in our cells) which seem to be affected with PD, the role of inflammation in the disease, the role of gut bacteria in alpha-synuclein build up, and the role oxygen plays in the breakdown of dopamine
This is where the comparison gets interesting and where supplementation strategy matters a lot