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First, it stimulates vascular endothelial growth factor expression

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Liver findings included lower liver weight, reduced triglyceride content and less severe histological features of steatosis and inflammatory-cell infiltration in treated mice

5-Amino-1MQ is a substrate-mimetic inhibitor that occupies the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)