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This deficiency can lead to megaloblastic anemia, where the body produces large, abnormal red blood cells that cannot function effectively, resulting in symptoms such as fatigue, weakness, and neurological issues

investigator-initiated educational grants from Janssen Canada, Otsuka Canada outside the submitted work

For individual adjustments and uncertainties especially during pregnancy, breastfeeding, or in the case of pre-existing conditions

Split dosing (dividing the daily amount into two injections, morning and evening) maintains more consistent tissue levels throughout the day

doi:10.1002/mnfr.201600328 Paiva C, Beserra B, Reis C, Dorea JG, Da Costa T, Amato AA