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17,500 MRP (incl

Abbreviations PH: partial hepatectomy GST: glutathione S- transferase GSH: glutathione TRAF2: tumor necrosis factor receptor-associated factor 2 ASK1: apoptosis signal regulating kinase 1 MAPK: mitogen-activated protein kinase JNK: c-jun N-terminal kinase ERK: extracellular signal regulated kinase MCM: minichromosome maintenance ROS: reactive oxygen species BrdU: 5-bromo-2'-deoxyuridine ATF: activating transcription factor CDK: cyclin-dependent kinase ALT: alanine aminotransferase AST: aspartate aminotransferase References Fausto N, Campbell JS, Riehle KJ

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AT004490) and from the US Department of Veterans Affairs (Merit Review no

Higher doses dont have any clinical basis and may increase risk