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The National Active and Retired Federal Employees Association (NARFE) has highlighted the Medicare GLP-1 Bridge as an important development for many federal retirees who previously found GLP-1 medications difficult to afford

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Researchers are now studying whether therapies can produce: Greater fat loss Better preservation of skeletal muscle Improved muscle quality Stable or improved strength Better physical function Reduced visceral and ectopic fat Improved cardiometabolic health A 2026 phase 2 trial, for example, tested the investigational myostatin-pathway drug apitegromab alongside tirzepatide and found greater short-term lean-mass preservation than tirzepatide alone

avoid afternoon/evening doses

Weeks 612: Cleaner body composition across the whole cycle