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A significant finding was the elevated levels of pyroglutamic acid in malignant cells, which was linked to the overexpression of CHAC1, resulting in the production of pyroglutamic acid and cysteinyl-glycine

3.4.2 Reduction in Oxidative Stress IF is a strong antioxidant because it helps the body fight off free radicals and reduces the amount of reactive oxygen species (ROS) that are made

dose-dependent response across 3, 6, and 9 mg arms Phase 3 T2D : HbA1c reductions up to 2.15% versus placebo in Chinese population trials Phase 1b/2 data : Earlier dose-finding studies establishing the efficacy and tolerability profile Global development : Ongoing clinical trials outside China, but no FDA approval or submission as of early 2026 Limitation : Primary clinical data from Chinese population

The study was performed according to The Code of Ethics of the World Medical Association (Declaration of Helsinki) for studies involving humans