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Outside primary metabolic indications, these mechanisms are also of interest for cardiometabolic risk reduction (such as waist circumference, triglycerides, and blood pressure) and for appetite control during lifestyle-based weight loss plans

Huberman and Ilardo examine the role of epigenetics in modifying gene expression across generations, the impact of genetic beliefs on physical performance, and the ethical considerations surrounding gene-editing technologies like CRISPR

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Closely related are RNS, a class of reactive molecules generated primarily from nitric oxide (NO) and nitrogen dioxide (NO)

This can result in conditions like melasma (dark patches on the face) and linea nigra (a dark line running down the abdomen)