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they are research directions where the compound has been useful as an experimental probe
Together, they address four of the five major systems disrupted in mood disorders: neurotransmitter balance, neuroinflammation, BDNF deficits, and HPA axis function
Studies demonstrate protection against brain edema, reduced inflammatory cytokines TNF- and IL-1, and enhanced neuronal survival following injury
Post hoc analysis of SUSTAIN 6 and PIONEER 6 trials suggests that people with type 2 diabetes at high cardiovascular risk treated with semaglutide experience more stable kidney function compared with placebo
See Supplementary Note for effects of -tocopherol
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