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Furthermore, inhibiting iron response element binding protein 2 (IREB2) using shRNA changes the expression of various iron genes (e.g., TRFC, FTH1, and FTL), affecting iron absorption, metabolism, and storage (80, 81)

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The ATFL receives limited baseline vascular supply compared to other ligaments, creating ischemic conditions that delay healing even in minor sprains

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Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer