Philp and colleagues (FASEB J, 2003, PMID 14500546) showed the LKKTETQ actin-binding motif at residues 17 to 23 is sufficient to promote endothelial cell migration in aortic ring and chorioallantoic assays, and Bock-Marquette and colleagues (Nature, 2004, PMID 15565145) reported integrin-linked kinase and Akt activation in mouse cardiac models
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Blood, hair, saliva and urine are all different for when it comes to how long alcohol can be detected in your system
TB-500's pharmacokinetics reflect its actin-binding behavior
This work lays a solid foundation for the development of sequential therapeutic agents that target vascular repair and provides robust scientific evidence to optimize strategies for the prevention and treatment of tissue injury across various contexts