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Na 48 weken bedroeg de gemiddelde gewichtsverandering (least-squares mean, vergeleken met placebo -2,1%): Bij de hoogste dosis had 60% van de deelnemers een gewichtsafname van 15% of meer bereikt, zonder dat de gewichtscurve op dat moment nog was afgevlakt

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Some prescription therapies (including tirzepatide) are dual-acting, meaning they work on two hormone pathwaysGLP-1 and GIPinstead of GLP-1 alone

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Research suggests that it may influence neural activity, vascular responses, and cellular pathways