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This evidence suggests prescribers are already prescribing these drugs off label and PBMs are not rejecting these claims

1 The MHRA has confirmed this, with the UK indication covering adults with a BMI of 30 or above, or adults with a BMI of 27 or above with at least one weight-related health condition

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In UK practice, presumptive positive results from immunoassay screening are confirmed using more specific techniques such as gas or liquid chromatography-mass spectrometry (GC-MS/LC-MS)