This indicated a lower influx of proline into the TCA cycle via the glutamate to -ketoglutarate route
Modifications in gene expression occur to yield an increase in the content of HSP [30, 31], proteins that act as molecular chaperones, being crucial in helping the cellular remodelling processes of denatured proteins, independent of the training response [89, 91]
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Magn Reson Med 30:672679 Raffa M, Barhoumi S, Atig F, Fendri C, Kerkeni A, Mechri A (2012) Reduced antioxidant defense systems in schizophrenia and bipolar I disorder