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Methods Drugs and media PZQ, NAC, Medium 199, HEPES (4-(2-hydroxyethyl)-1-piperazine ethane sulfonic acid) (1M), l-glutamine, penicillin and streptomycin, Hanks balanced salt solution (HBSS), and amphotericin B were purchased from Sigma-Aldrich (Lisboa, Portugal)

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(Lausanne) 14

That said, extensive research including controlled studies and mechanistic research shows that ALA and ALC affect mitochondrial function, antioxidant pathways, and nerve metabolism

But at the doses used, the net effect on blood sugar is positive because the GLP-1 and GIP activity dominates, and the glucagon activation primarily drives fat burning rather than glucose release