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Inflammation and the gut-brain connection Cigarette smoke increases low-grade inflammation in the intestines. Since IBS is strongly influenced by the gut-brain axis (the two-way communication between the gut and the nervous system), this extra stress can worsen how signals are processed, leading to more discomfort and unpredictability

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Participants were questioned about their headache experiences over the preceding six months, with frequent headaches defined as occurring more than once per week

E-liquid with extracted nicotine salt is known to more closely emulate the nicotine absorption rate of traditional methods while providing a smoother inhale

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