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First-line: nonpharmacological measures (e.g., high-fiber diet, increased fluid intake, and exercise) and/or trial of fiber supplementation (i.e., bulk-forming laxatives) [5] [22] Second-line: step-wise pharmacotherapy with laxatives from other classes [6] [13] [22] Begin with an osmotic laxative

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Patients should be aware that ongoing treatment is typically required to preserve the benefits. Nausea and Tolerance One of the common side effects when starting GLP-1 receptor agonists is nausea

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They may adjust your dosage or provide additional recommendations to help manage your symptoms effectively