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Single-target drugs often produce inconsistent results because biological systems are interconnected

It was originally identified as a fragment derived from a larger protein found in human gastric juice, which sparked early scientific interest due to its unusual stability and biological activity under experimental conditions

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GLP-1 agonists preserve mitochondrial function in cardiomyocytes To assess the effects of GLP-1 agonists on mitochondrial function, we performed experiments on primary cardiomyocytes exposed to angiotensin II (Ang II) to mimic pathological stress conditions

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