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GHK-Cu Cream works locally within the skin layers (epidermis and dermis)

doi:10.1016/S0736-0266(03)00110-4 Goldstein AL, Hannappel E, Sosne G, Kleinman HK

2024 doi: 10.1007/s12020-024-04033-6

It is also banned by WADA (World Anti-Doping Agency) and ASADA, so competitive athletes can (and have) received bans for using it