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GPX1 polymorphism with risk of diabetes and obesity in different populations [64, 65, 66, 67, 68]

Small Maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:quinone oxidoreductase1 gene

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These findings dont rule out its use, but they do mean close monitoring matters, especially if you already have heart disease or risk factors