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[DOI] [PMC free article] [PubMed] [Google Scholar] Hu L, Guo Y, Song L, Wen H, Sun N, Wang Y, et al

Single-mechanism drugs target one cytokine or one receptor

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Studies have shown [11]: Prevention of gastric lesions when co-administered with NSAIDs Healing of existing NSAID-induced damage Protection of both upper and lower GI tract Preservation of intestinal permeability This is particularly significant given that millions of people take NSAIDs regularly, often experiencing GI side effects