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It was correlation

Conlon N, et al

FoxO proteins and cardiac pathology

They convert nutrients from food into ATP (adenosine triphosphate) the energy currency your body uses for everything from thinking to moving to breathing

A pathological excess of ROS - as is associated with CYP induction (65), ultraviolet irradiation, xanthine oxidase activity under conditions of ischaemia-reperfusion, and so on - threatens cell viability by jettisoning just those homeostatic mechanisms that physiological oxidative stress secures (21)