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org/10.3390/ijms23052717 Zafar, M

Jul 18 2024;391(3):247-258

Haloxyl (N-hydroxysuccinimide and chrysin combination) targets vascular dark circles through different pathway enhancing hemoglobin metabolism clearing accumulated blood deposits creating discoloration, strengthening capillary walls reducing leakage and pooling, and anti-inflammatory effects minimizing swelling and related darkness

For BSO group, a week later, mice received intraperitoneal administration of 750 mg/kg of body weight BSO (B113387, Aladdin) in phosphate-buffered saline (pH 7.4) once a day for two weeks 25